Synthesis of Biaryls Having a Piperidylmethyl Group Based on Space Integration of Lithiation, Borylation and Suzuki-Miyaura Coupling
Takahashi, Y.; Ashikari, Y.; Takumi, M.; Shimizu, Y.; Jiang, Y.; Higuma, R.; Ishikawa, S.; Sakaue, H.; Shite, I.; Maekawa, K.; Aizawa, Y.; Yamashita, H.; Yonekura, Y.; Colella, M.; Luisi, R.; Takegawa, T.; Fujita, C.; Nagaki, A.
Eur. J. Org. Chem. 2020, 618–622.
DOI: 10.1002/ejoc.201901729
An aryllithium bearing piperidylmethyl group was generated, borylated, and reacted with aryliodides to generate nitrogen-containing biaryls.
