Generation of carbonyl anion and its application for three-component synthesis of alpha-ketomides

publication
publication

Generation and Reaction of Carbamoyl Anions in Flow: Applications in the Three-Component Synthesis of Functionalized alpha-Ketoamides.
Nagaki, A.; Takahashi, Y.; Yoshida, J.
Angew. Chem., Int. Ed. 2016, 55, 5327–5331
DOI: 10.1002/anie.201601386

Generation of carbamoyl lithium species, a carbonyl anion, and its three-component reaction for the synthesis of α-keto amides.