Three-Component Coupling Based on Flash Chemistry. Carbolithiation of Benzyne with Functionalized Aryllithiums Followed by Reactions with Electrophiles
Nagaki, A.; Ichinari, D.; Yoshida, J.
J. Am. Chem. Soc. 2014, 136, 12245–12248.
DOI: 10.1021/ja5071762
A three-component reaction involving benzyne generation, carbolithiation, and reaction with an electrophile. The 2-bromophenyl lithium species and aryl lithium species are generated separately.
