Flash Synthesis of TAC-101 and Its Analogues from 1,3,5-Tribromobenzene Using Integrated Flow Microreactor Systems.
Nagaki, A.; Imai, K.; Kim, H.; Yoshida, J.
RSC Adv. 2011, 1, 758–760.
DOI: 10.1039/C1RA00377A
Sequential halogen-lithium exchange reaction and electrophilic reactions enabled rapid synthesis for drug precursor
