Reactions of organolithiums with dialkyl oxalates to synthesize alpha-ketoester

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Reactions of Organolithiums with Dialkyl Oxalates. A Flow Microreactor Approach to Synthesis of Functionalized alpha-Keto Esters
Nagaki, A.; Ichinari, D.; Yoshida, J.
Chem. Commun. 2013, 49, 3242–3244.
DOI: 10.1039/c3cc40392k

Reaction of an aryl lithium with dialkyl oxalate was achieved by sequential reaction control to synthesize α-keto esters.