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Mono lithiation of dibromopyridines

publication
2024.08.16
publication
flash synthesisintegrationN-containno low tempreactive intermediate

Flow Microreactor Synthesis of Disubstituted Pyridines from Dibromopyridines via Br/Li Exchange without Using Cryogenic Conditions.
Nagaki, A.; Yamada, S.; Doi, M.; Tomida, Y.; Takabayashi, N.; Yoshida, J.
Green Chem. 2011, 13, 1110–1113.
DOI: 10.1039/C0GC00852D

Mono lithiation of dibromopyridines at mild conditions was achieved.

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Mono lithiation of dibromopyridines

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