Flash Functional Group-Tolerant Biaryl-Synthesis Based on Integration of Lithiation, Zincation and Negishi Coupling in Flow
Ashikari, Y.; Guan, K.; Nagaki, A.
Front. Chem. Eng. 2022, 4, 964767.
DOI: 10.3389/fceng.2022.964767
Generation of functionalized aryl lithium species, zincation, and integration of the Negishi coupling reaction for the synthesis of biaryls. This process enables the synthesis of biaryls with boryl groups.
