Synthesis of Functionalized Ketones from Acid Chlorides and Organolithiums by Extremely Fast Micromixing.
Nagaki, A.; Sasatsuki, K.; Ishiuchi, S.; Miuchi, N.; Takumi, M.; Yoshida, J.
Chem. Eur. J. 2019, 25, 4946–4950.
DOI: 10.1002/chem.201900743
A flow microreactor suppresses overreaction in the reaction of organolithium species with a carboxylic acid chloride, achieving ketone synthesis.
